{
  "package" : "hl7.terminology.r4@6.3.0",
  "definition" : "A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective.\\r\\n\\r\\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\\r\\n\\r\\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.",
  "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
  "property" : [ {
    "_uri" : "http://hl7.org/fhir/concept-properties#status",
    "code" : "status",
    "valueCode" : "active"
  }, {
    "_uri" : "http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id",
    "code" : "internalId",
    "valueCode" : "23620"
  }, {
    "_uri" : "http://hl7.org/fhir/concept-properties#parent",
    "code" : "subsumedBy",
    "valueCode" : "S"
  } ],
  "codesystem" : "72be8320-cd3f-5241-97c5-7f393677c255",
  "concept_id" : "354f1350-cfe0-56fe-add2-d0391fdbf494",
  "ancestors" : {
    "S" : 1,
    "SYN-S" : 0,
    "_ObservationInterpretationSusceptibility" : 2
  },
  "id" : "f2eccb41-b795-4812-867f-23d5e5422d78",
  "code" : "SYN-S",
  "display" : "Synergy - susceptible",
  "version" : "3.0.0"
}